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Selected Publication:

Type of publication: Journal Article
Type of document: Full Paper

Year: 1998


Title: Membrane fusion mediated by ricin and viscumin.

Source: Biochim Biophys Acta (1371), 1 11-16.

Authors Vetmeduni Vienna:

Pohl Elena

The ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle-vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity. Herein, fusion is hypothesized to allow the RIPs to leak across endocytic vesicles to approve their access to cytoplasmic ribosomes. (C) 1998 Elsevier Science B.V.

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