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Type of publication: Journal Article
Type of document: Full Paper

Year: 2010

Authors: Gabler, C; Fischer, C; Drillich, M; Einspanier, R; Heuwieser, W

Title: Time-dependent mRNA expression of selected pro-inflammatory factors in the endometrium of primiparous cows postpartum.

Source: Reprod Biol Endocrinol. 2010; 8:152



Authors Vetmeduni Vienna:

Drillich Marc

Vetmed Research Units
University Clinic for Ruminants, Clinical Unit of Herd Management in ruminants


Abstract:
Inflammatory processes and infections of the uterine wall must be accepted as a physiological event in dairy cows after calving. This might result in clinical or subclinical endometritis which is assumed to impair reproductive performance in the current lactation. Several cytokines and acute phase proteins have been discussed as local and systemic mediators of these inflammatory processes. The aim of the present study was to investigate the endometrial mRNA expression of the chemokine CXC ligand 5 (CXCL5), interleukin 1β (IL1B), IL6, IL8, tumour necrosis factor alpha (TNF), prostaglandin-endoperoxide synthase 2 (PTGS2) and haptoglobin (HP) in the postpartum period.

Keywords Pubmed: Animals
Cattle
Chemokine CXCL5/biosynthesis
Cyclooxygenase 2/biosynthesis
Cytokines/biosynthesis*
Endometritis/metabolism
Endometrium/metabolism*
Female
Haptoglobins/biosynthesis
Immunity, Innate/physiology
Interleukin-1beta/biosynthesis
Interleukin-8/biosynthesis
Neutrophils/metabolism
Parity
Postpartum Period/immunology
Postpartum Period/metabolism
Pregnancy
RNA, Messenger/metabolism*
Tumor Necrosis Factor-alpha/biosynthesis
Uterus/microbiology


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