University of Veterinary Medicine Vienna - Research portal

Diagrammed Link to Homepage University of Veterinary Medicine, Vienna

Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 2011

Author(s): Binter, C; Khol-Parisini, A; Gerner, W; Schäfer, K; Hulan, HW; Saalmüller, A; Zentek, J

Title: Effect of maternally supplied n-3 and n-6 oils on the fatty acid composition and mononuclear immune cell distribution of lymphatic tissue from the gastrointestinal tract of suckling piglets.

Source: Arch Anim Nutr. 2011; 65(5):341-353



Authors Vetmeduni Vienna:

Binter Claudia
Gerner Wilhelm
Khol Annabella
Saalmüller Armin
Zentek Jürgen

Vetmed Research Units
Institute of Animal Nutrition and Functional Plant Compounds
Institute of Immunology


Abstract:
Fatty acids are essential for immune cell function. Maternal dietary fatty acid supply influences body fat composition of their offspring. As a first step to study immunonutritional interactions at an early age of pigs, four sows were fed a diet containing sunflower oil or oil from seal blubber during pregnancy and lactation. Corresponding piglets were sacrificed at three consecutive time points in the suckling period and their mesenteric lymph nodes and spleen were analysed by gas chromatography for levels of fatty acid. At the same time mononuclear cells of these organs and of the intestinal lymphoid tissue from the jejunum were isolated and subpopulations characterised by flow cytometry. Levels of fatty acids from the lymphatic organs of the piglets were significantly influenced by the maternal diet. The concentration of the fatty acids 20:5n-3, 22:5n-3 and 22:6n-3 were higher in the spleen and mesenteric lymph node of piglets suckled to sows of the test diet. Additionally, suckling time affected the levels of some long chain polyunsaturated fatty acids. Dietary effects were seen on some subpopulations including CD4-CD8alpha+ lymphocytes of the mesenteric lymph nodes and CD4+CD8alpha+ lymphocytes of the lamina propria, which were higher in the group fed seal blubber oil. The levels of CD21+ B-cells were higher in the group fed sunflower oil. The results indicate that the maternal diet and suckling time affect the fatty acid status of the investigated lymphatic tissues of piglets, but may have minor effects on the investigated lymphocyte subpopulations.

Keywords Pubmed: Animal Feed
Animal Nutritional Physiological Phenomena
Animals
Animals, Suckling/physiology*
Diet/veterinary
Fatty Acids, Omega-3/chemistry
Fatty Acids, Omega-3/pharmacology*
Fatty Acids, Omega-6/chemistry
Fatty Acids, Omega-6/pharmacology*
Female
Gastrointestinal Tract/cytology*
Gastrointestinal Tract/drug effects
Lymphoid Tissue/cytology
Lymphoid Tissue/drug effects*
Maternal Nutritional Physiological Phenomena
Pregnancy
Swine/metabolism*


© University of Veterinary Medicine ViennaHelp and Downloads