University of Veterinary Medicine Vienna - Research portal

Diagrammed Link to Homepage University of Veterinary Medicine, Vienna

Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 1998

Author(s): Pescovitz, MD; Book, BK; Aasted, B; Dominguez, J; Bullido, R; Trebichavsky, I; Novikov, B; Valpotic, I; Nielsen, J; Arn, S; Sachs, DH; Lunney, JK; Boyd, PC; Walker, J; Lee, R; Petrinec, N; Saalmüller, A

Title: Analyses of monoclonal antibodies reacting with porcine wCD6: results from the Second International Swine CD Workshop.

Source: Vet Immunol Immunopathol (60), 3-4 285-289.



Authors Vetmeduni Vienna:

Saalmüller Armin


Abstract:
Among the 57 monoclonal antibodies analyzed within the T-cell group of the Second International Swine CD Workshop, one mAb fell within cluster T14a that included the CD6 standard a38b2 (No. 175). The new mAb MIL8 (No. 082) and a38b2 both precipitated from activated T-cells a 150 kDa monomeric protein. Staining patterns on the various cell types were similar. There was no inhibition of binding of either mAb to peripheral blood T-cells with the opposite mAb. The new mAb, MIL8, reacts with a separate epitope on porcine wCD6. (C) 1998 Elsevier Science B.V.

Keywords Pubmed: Animals - : Antibodies, Monoclonal - analysis : Antigen-Antibody Reactions - analysis : Antigens, CD - biosynthesis : Antigens, Differentiation, T-Lymphocyte - biosynthesis : Flow Cytometry - biosynthesis : Swine - immunology : T-Lymphocyte Subsets - immunology

© University of Veterinary Medicine ViennaHelp and Downloads