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Publication type: Journal Article
Document type: Full Paper

Year: 1994

Author(s): Saalmüller, A; Aasted, B; Canals, A; Dominguez, J; Goldman, T; Lunney, JK; Maurer, S; Pauly, T; Pescovitz, MD; Pospisil, R

Title: Analyses of monoclonal antibodies reactive with porcine CD6.

Source: Vet Immunol Immunopathol (43), 1-3 243-247.

Authors Vetmeduni Vienna:

Saalmüller Armin

Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.

Keywords Pubmed: Animals - : Antibodies, Monoclonal - analysis : Antibody Specificity - immunology : Antigens, CD - immunology : Antigens, Differentiation, T-Lymphocyte - immunology : Epitopes - immunology : Flow Cytometry - veterinary : Swine - immunology : T-Lymphocyte Subsets - immunology

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