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Type of publication: Diploma Thesis
Type of document:

Year: 2012

Authors: Dockal, Alexandra

Title: Phytochemische Untersuchungen an Wegerich-Arten, die als Nahrungsergänzungsmittel genutzt werden.

Other title: Phytochemische Untersuchungen an Wegerich-Arten, die als Nahrungsergänzungsmittel genutzt werden

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 52.


Chizzola Remigius

Zebeli Qendrim

Vetmed Research Units:
Institute of Animal Nutrition and Functional Plant Compounds

Graduation date: 24.10.12

Project(s): PLANT food supplements: Levels of Intake, Benefit and Risk Assessment

Herbal drugs are used in human and veterinary medicine as drugs, phytopharmaceuticals or food and feed supplements. Even in traditional medicine various plants are still used. The iridoid-glycosid aucubin is widespread in the genus Plantago and has antibacterial, antiinflammatory, spasmolytic and liver-protective properties. In contrast to aucubin, the iridoid-glycosid catalpol is present only in a few plantain species. The phenylpropanoid verbascoside has been observed quite often in plantain plants and has antioxidant and antibacterial properties. As part of this thesis twelve different Plantago species of different origins were analyzed by GC/FID for the presence of aucubin and catalpol. For the analysis of verbascoside a HPLC method was used. In all available species, aucubin and catalpol as well as verbascosid were studied (Tab. 2) in all plant parts (leaves, roots and stems with flowers/fruits). The results showed that in ten of twelve analysed Plantago species (P. major, P. cornuti, P. maritima, P. subulata, P. media, P. lanceolata, P. lagopus, P. albicans, P. afra and P. sempervirens) aucubin was present in the leaves. Even in the roots of P. major, P. cornuti, P. subulata, P. media, P. lagopus, P. albicans and P. sempervirens aucubin was present. Catalpol could be detected only in P. lanceolata and P. lagopus in the leaves and in the roots. In all twelve Plantago-species verbascoside could be detected both in the leaves and in the roots. The total amounts (mg/g dry mass) of these ingredients varied from species to species. Aucubin ranged from 0.4 mg/g in the leaves of P. major to 14.5 mg/g in the leaves of P. lanceolata. In the roots the content of aucubin was between 0.8 mg/g in P. sempervirens and 42.9 mg/g in P. cornuti. Similarly verbascoside showed a wide concentration range. It varied from 3.2 mg/g in the leaves of P. lagopus to 26.4 mg/g in the leaves of P. albicans and in the roots from 1.1 mg/g in P. lagopus to 30.0 mg/g in P. cornuti. In the course of this thesis it was found, that the instability of aucubin in methanolic extracts was clearly visible within 24 hours.

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