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Publication type: Journal Article
Document type: Full Paper

Year: 2017

Author(s): Glatthaar-Saalmüller, B; Mair, KH; Saalmüller, A

Title: Antiviral activity of aspirin against RNA viruses of the respiratory tract-an in vitro study.

Source: Influenza Other Respir Viruses. 2017; 11(1):85-92



Authors Vetmeduni Vienna:

Glatthaar-Saalmüller Bernadette
Mair Kerstin
Saalmüller Armin

Vetmed Research Units
Institute of Immunology


Abstract:
Aspirin (acetylsalicylic acid) has been used for more than 115 years in medicine. Research exists to show that aspirin has antiviral effects in vitro, for example, by blocking influenza virus propagation via NF-κB inhibition when used at high concentrations and short-term incubation steps. The aim of this study was to confirm the antiviral activity of aspirin against influenza virus and further elucidate the activity of aspirin against other respiratory viruses.

Keywords Pubmed: Antiviral Agents/pharmacology*
Aspirin/pharmacology*
Enterovirus/drug effects
Humans
Influenza A Virus, H1N1 Subtype/drug effects*
Influenza A virus/drug effects
Microbial Sensitivity Tests
RNA Viruses/drug effects*
Respiratory Syncytial Virus, Human/drug effects
Respiratory System/virology*
Rhinovirus/drug effects*
Viral Plaque Assay


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