To appreciate the significance of sales data of antibiotics, data on antibiotic consumption (which were collected for selected food-producing animals within the representative VetCAb pilot study in Germany in 2011) were extrapolated for the total German animal population, and subsequently compared to the antibiotic sales data, which were collected throughout Germany in 2011 for the first time and which were published by the Federal Office of Consumer Protection and Food Safety (BVL). The extrapolation was realized based on the average dosage and the number of treatment units determined in the VetCAb pilot project for each active ingredient and animal species. It was extrapolated that 1302 tons of antimicrobial substances were consumed for treating cattle, pigs and broilers - this amount is accompanied by the amount of 1706 tons sold for all animal species. In Germany, tetracyclines and beta-lactams are the most commonly used and sold antimicrobial drugs. In third place are the potentiated sulfonamide, in fourth and fifth place, macrolides and polypeptides. To describe and evaluate the antibiotic usage for the several food-producing animals, detailed information is needed. Therefore, the number of treatments per active ingredient per animal and per day (treatment unit), and the number of treatment days per active ingredient per animal (treatment frequency) were calculated in the VetCAb project. These values represent scientifically collected orientation values for the treatment frequency of food-producing animal with antimicrobial substances in Germany. For example, a fattening pig is treated at 4.2 days (median) with one active ingredient within its 115-day fattening period. A dairy cow is treated at 3.5 days with one active ingredient within one year. A broiler is treated at 10 days with one active ingredient within its 39-day production period.