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Selected Publication:

Type of publication: Journal Article
Type of document: Full Paper

Year: 2018

Authors: Karamendin, KO; Kydyrmanov, AI; Kasymbekov, ET; Daulbayeva, KD; Sayatov, MH; Fereidouni, S

Title: Application Of Massive Parallel Sequencing For The Investigation Of Wild Birds Viruses.

Source: Bull Natl Acad Sci P 4(374): 13-17.

Authors Vetmeduni Vienna:

Fereidouni Sasan

Vetmed Research Units
Research Institute of Wildlife Ecology, Conservation Medicine


Abstract:
Identification of viral pathogens is of great importance for the diagnostics of infectious diseases in humans and animals Almost all outbreaks of dangerous infections in the last two decades have been caused by new viruses, most of which originated from a natural reservoir. Experimental studies on avian paramyxovirus (APMV) of serotype 1 have shown that wild birds can spread and introduce mild or non-pathogenic virus variants into the poultry population, which, after several passages in the organism of susceptible birds, often acquire highly pathogenic properties. Using the new technology of massive parallel sequencing, information on the genetic structure of wild bird viruses belonging to the Paramyxoviridae family was obtained. The high efficiency of the method is shown, which allows simultaneous sequencing of the complete genomes of viruses without prior knowledge of their belonging to any family. The data obtained will allow us to expand our knowledge of the course of the natural evolution of migratory bird viruses.


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