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Publication type: Journal Article
Document type: Short Communication

Year: 2019

Author(s): Meszaros, G; Fornara, M; Reyer, H; Wimmers, K; Solkner, J; Brem, G; Sermyagin, A; Zinovieva, N

Title: Elevated haplotypes frequencies reveal similarities for selection signatures in Western and Russian Simmental populations.

Source: J Cent Eur Agric 20(1): 1-11.



Authors Vetmeduni Vienna:

Brem Gottfried

Vetmed Research Units
Unit of Reproductive Biology


Abstract:
This paper shows a straightforward, but surprisingly effective approach to detect genomic regions of importance, illustrated on two Simmental cattle populations. Medium density genomic data of 42 German/Austrian (denoted as "Western") and 38 Russian Simmental cattle were used to identify the most frequent haplotypes within the two populations. The haplotypes were defined as non-overlapping segments of ten single nucleotide ploymorphisms (SNP). The phasing was done with the SHAPEIT software, with a follow up analysis of haplotypes using the GHap package. Despite the low sample size a number of high frequency haplotypes could be identified accross the whole genome. The identified genes residing direcly in these high frequency haplotypes were extremely relevant for the dual purpose Simmental cattle. A large part of these genes influenced growth rate and carcass traits, others were relevant for the milk production. A smaller proportion was connected to the reproduction, immune system and cellular processes, with indirect influence on production traits.


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