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Publication type: Journal Article
Document type: Full Paper

Year: 2019

Author(s): Grilz-Seger, G; Druml, T; Neuditschko, M; Mesarińć, M; Cotman, M; Brem, G

Title: Analysis of ROH patterns in the Noriker horse breed reveals signatures of selection for coat color and body size.

Source: Anim Genet. 2019; 50(4):334-346



Authors Vetmeduni Vienna:

Brem Gottfried
Druml Thomas
Grilz-Seger Gertrud

Vetmed Research Units
Institute of Animal Breeding and Genetics, Unit of Reproductive Biology


Project(s): Automatisation der Phänotypisierungen von Exterieur-und Bewegungsmerkmalen und genomische Analysen beim Lipizzaner


Abstract:
Overlapping runs of homozygosity (ROH islands) shared by the majority of a population are hypothesized to be the result of selection around a target locus. In this study we investigated the impact of selection for coat color within the Noriker horse on autozygosity and ROH patterns. We analyzed overlapping homozygous regions (ROH islands) for gene content in fragments shared by more than 50% of horses. Long-term assortative mating of chestnut horses and the small effective population size of leopard spotted and tobiano horses resulted in higher mean genome-wide ROH coverage (S


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