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Type of publication: Journal Article
Type of document: Full Paper

Year: 2019

Authors: Grilz-Seger, G; Druml, T; Neuditschko, M; Mesarič, M; Cotman, M; Brem, G

Title: Analysis of ROH patterns in the Noriker horse breed reveals signatures of selection for coat color and body size.

Source: Anim Genet. 2019; 50(4):334-346

Authors Vetmeduni Vienna:

Brem Gottfried
Druml Thomas
Grilz-Seger Gertrud

Vetmed Research Units
Institute of Animal Breeding and Genetics, Unit of Reproductive Biology

Project(s): Automatisation der Phänotypisierungen von Exterieur-und Bewegungsmerkmalen und genomische Analysen beim Lipizzaner

Genetic analyses of coat colors with regard to practical breeding andconservation genetics in the Lipizzan, Noriker horse breed and theWeiße Barockesel breed

Overlapping runs of homozygosity (ROH islands) shared by the majority of a population are hypothesized to be the result of selection around a target locus. In this study we investigated the impact of selection for coat color within the Noriker horse on autozygosity and ROH patterns. We analyzed overlapping homozygous regions (ROH islands) for gene content in fragments shared by more than 50% of horses. Long-term assortative mating of chestnut horses and the small effective population size of leopard spotted and tobiano horses resulted in higher mean genome-wide ROH coverage (S

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