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Publication type: Journal Article
Document type: Full Paper

Year: 2019

Author(s): Lagler, J; Mitra, T; Schmidt, S; Pierron, A; Vatzia, E; Stadler, M; Hammer, SE; Mair, KH; Grafl, B; Wernsdorf, P; Rauw, F; Lambrecht, B; Liebhart, D; Gerner, W

Title: Cytokine production and phenotype of Histomonas meleagridis-specific T cells in the chicken.

Source: Vet Res. 2019; 50(1):107



Authors Vetmeduni Vienna:

Gerner Wilhelm
Grafl Beatrice
Hammer Sabina
Lagler Julia
Liebhart Dieter
Mair Kerstin
Mitra Taniya
Pierron Alix
Schmidt Selma
Stadler Maria
Vatzia Eleni
Wernsdorf Patricia

Vetmed Research Units
University Clinic for Poultry and Fish Medicine, Clinical Unit of Poultry Medicine
Institute of Immunology


Project(s): Phenotype and cytokine production of Histomonas meleagridis-specific T cells isolated from chickens and turkeys infected with the parasite or vaccinated against histomonosis


Abstract:
The protozoan parasite Histomonas meleagridis is the causative agent of the re-emerging disease histomonosis of chickens and turkeys. Due to the parasite"s extracellular occurrence, a type-2 differentiation of H. meleagridis-specific T cells has been hypothesized. In contrast, a recent study suggested that IFN-γ mRNA


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