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Type of publication: Journal Article
Type of document: Full Paper

Year: 2020

Authors: EFSA Panel on Biological Hazards (BIOHAZ), ; Koutsoumanis, K; Allende, A; Bolton, DJ; Bover-Cid, S; Chemaly, M; Davies, R; De Cesare, A; Herman, LM; Hilbert, F; Lindqvist, R; Nauta, M; Peixe, L; Ru, G; Simmons, M; Skandamis, P; Suffredini, E; Andreoletti, O; Griffin, J; Spiropoulos, J; Ortiz-Pelaez, A; Alvarez-Ordóñez, A

Title: Potential BSE risk posed by the use of ruminant collagen and gelatine in feed for non-ruminant farmed animals.

Source: Efsa J. 2020; 18(10): 6267

Authors Vetmeduni Vienna:

Hilbert Friederike

EFSA was requested to estimate the cattle bovine spongiform encephalopathy (BSE) risk (C-, L- and H-BSE) posed by ruminant collagen and gelatine produced from raw material fit for human consumption, or from material classified as Category 3 animal by-products (ABP), to be used in feed intended for non-ruminant animals, including aquaculture animals. Three risk pathways (RP) were identified by which cattle could be exposed to ruminant feed cross-contaminated with ruminant collagen or gelatine: 1) recycled former foodstuffs produced in accordance with Regulation (EC) No 853/2004 (RP1), 2) technological or nutritional additives or 3) compound feed, produced either in accordance with Regulation (EC) No 853/2004 (RP2a) or Regulation (EU) No 142/2011 (RP2b). A probabilistic model was developed to estimate the BSE infectivity load measured in cattle oral ID 50 (CoID 50)/kg, in the gelatine produced from the bones and hide of one infected animal older than 30 months with clinical BSE (worst-case scenario). The amount of BSE infectivity (50th percentile estimate) in a member state (MS) with negligible risk status was 7.6 × 10-2 CoID 50/kg, and 3.1 × 10-4 CoID 50/kg in a MS with controlled risk status. The assessment considered the potential contamination pathways and the model results (including uncertainties) regarding the current epidemiological situation in the EU and current statutory controls. Given the estimated amount of BSE infectivity to which cattle would be exposed in a single year, and even if all the estimated undetected BSE cases in the EU were used for the production of collagen or gelatine (either using raw materials fit for human consumption or Category 3 ABP raw materials), it was concluded that the probability that no new case of BSE in the cattle population would be generated through any of the three RP is 99-100% (almost certain).© 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

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